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OxyContin Prescriptions
Oxycodone hydrochloride Painkiller Info
OxyContin (oxycodone HCl) tablets are a controlled-release oral formulation
of oxycodone hydrochloride indicated for the management of moderate to severe
pain when a continuous, around-the-clock analgesic is needed for an extended
period of time. The two highest-strength OxyContin tablets -- 80 and 160 milligrams
--are dangerous for anyone who has not already developed a tolerance for narcotics.
If you have been prescribed one of these strengths, do not give the tablets
to anyone else; they could impair respiration and lead to death. Oxycodone is
a pure agonist opioid whose principal therapeutic action is analgesia. Other
members of the class known as opioid agonists include substances such as morphine,
hydromorphone, fentanyl, codeine, and hydrocodone. Pharmacological effects of
opioid agonists (i.e. OxyContin) include anxiolysis, euphoria, feelings of relaxation,
respiratory depression, constipation, miosis, and cough suppression, as well
as analgesia. Like all pure opioid agonist analgesics, with increasing doses
there is increasing analgesia, unlike with mixed agonist/antagonists or non-opioid
analgesics, where there is a limit to the analgesic affect with increasing doses.
With pure opioid agonist analgesics, there is no defined maximum dose; the ceiling
to analgesic effectiveness is imposed only by side effects, the more serious
of which may include somnolence and respiratory depression. Be sure to swallow
OxyContin tablets whole. If broken, crushed, or chewed, the tablets quickly
release a potentially fatal overdose of oxycodone. Abusing OxyContin by chewing
the tablets, snorting crushed tablets, or dissolving and injecting their contents
can slow down or stop breathing and lead to death. Injecting OxyContin can also
kill the tissue around the injection site and trigger heart and lung problems.
Oxycodone, like morphine and other opioids used in pain suppression, can be
abused and is subject to criminal diversion.
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